In a medium microwave-safe bowl, combine chocolate chips, heavy cream, and butter.
Microwave on high for 1-2 minutes, or until heavy cream just begins to boil.
Whisk until the chocolate and butter are completed melted, and the mixture is smooth.
Place in the refrigerator for 10-15 minutes to allow it to thicken.
Using a spoon or cookie scoop, scoop a 1-inch ball out of the center of each cupcake.
Spoon a rounded teaspoonful of ganache into the center of the hole of each cupcake.